Your doctor will combine a short term and long term medication options for ideal results.

Short-term pain relief medications

These will help you during gout attacks, when you are most in pain, discomfort and need relief.

  • Colchicine: designed to block inflammation and reduce swelling. Has shown to reduce gout flare-ups by 85%. So if you feel a gout attack coming up, it’s a good way to stop/prevent the attack.
  • NSAIDs (Nonsteroidal anti-inflammatory drugs): Over the counter medications: Mortin, Advil, Aleve available at your local pharmacy. Other medications of higher dose will require prescription from your doctor: Volatren, Celebrex, Indocin, Anaprox. NSAIDs will help reduce pain and swelling by blocking the enzymes and proteins involved in the inflammatory process.
  • Corticosteroids: A good option if you are unable to tolerate NSAIDs or colchicine. Can be taken as a pill or injected into the muscle where the joint is affected. Prednisone is the most commonly prescribed corticosteroid. Corticosteroids will help reduce pain and swelling from inflammation providing almost immediate relief from gout symptoms. A special note if you are diabetic, you may experience changes in your blood sugar levels when taking corticosteroids.

Long-term preventative medications

Preventative medications help keep uric acid levels healthy as well to prevent any future gout flare-ups or attacks.

*These medications are NOT designed to be taken while having a gout attack, and can even worsen the condition.

  • Allopurinol: The most popular gout medication. Allopurinol inhibits the activity of xanthine oxidase enzyme which is involved in your purine metabolism. Basically reducing production of uric acid in your body.
  • Febuxostat: it functions the same way as allopurinol by decreasing uric acid levels in the blood. Febuxostat goes by the brand name Uloric. It is metabolized by the liver, so it’s considered safe for those suffering from kidney disease.
  • Probenecid: goes by the brand name of Benemid and Probalan, works as a preventive by reducing uric acid. It is mostly prescribed to gout sufferers whose kidneys don’t properly excrete uric acid so probenecid can help them increase excretion.
  • Lesinurad (Zurampic): It’s often being used in combination with allopurinol to treat gout in those patients that can’t achieve their uric acid targets will only allopurinol.
  • Pegloticase: a medication for those who are intolerant to all other gout medication options. It is administered via intravenous infusion every two weeks and is considered a last resort option. It goes by the brand name Krystexxa.


Combine medications with proper diet and lifestyle changes for a better gout free future.